Uses | • pain relief (available on site) |
Contraindications, drug interactions or cautions | Contraindications • severe hepatic impairment or severe active liver disease Drug interactions • cholestyramine, probenecid, alcohol, carbamazepine, isoniazid, lamotrigine Cautions • limit acetaminophen dose to <4 g/day (adults) • use with caution in patients with alcoholic liver disease, known G6PD deficiency, hepatic impairment, or active liver disease. |
Adverse Effects (common and severe) | • nausea • vomiting • acute liver failure • fatal skin reactions including Stevens-Johnson syndrome and • toxic epidermal necrolysis |
Instructions and dose (initial; typical) | 325-650mg three or four times a day |
Monitoring | • liver enzymes for chronic use |
Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2015) |