amoxicillin
| Uses | • bacterial infections (ear; nose; throat; genitourinary; lower respiratory tract; skin) • available on site |
| Contraindications, drug interactions or cautions | Contraindications • serious hypersensitivity to amoxicillin (e.g., anaphylaxis, Stevens-Johnson syndrome) or to other beta-lactams Drug interactions • anticoagulants, macrolides, tetracyclines, sulfonamides, oral contraceptives, methotrexate Cautions • dosage adjustment recommended for patients with renal impairment • prolonged use may result in fungal or bacterial superinfection, including C. difficile-associated diarrhea and pseudomembranous colitis |
| Adverse Effects (common and severe) | • nausea • vomiting • skin rash • clostridium difficile-associated diarrhea |
| Instructions and dose (initial; typical) | indication-specific dosing (usual oral dosing range for mild to moderate infection: 250 every 8 hours or 500 mg every 12 hours) |
| Monitoring | • monitor for signs of anaphylaxis during first dose |
| Source of Suggestion | WHO Model List of Essential Medicines (Added on August 2015) |