efavirenz
| Uses | • antiviral: HIV-1 infection |
| Contraindications, drug interactions or cautions | Contraindications • hypersensitivity to efavirenz (Stevens-Johnson syndrome, erythema multiforme, toxic skin eruptions) Drug interactions • cabamazepine, itraconzole, ketoconazole, nisoldipin |
| Adverse Effects (common and severe) | • dizziness • fever • depression • insomnia • skin rash • increased serum cholesterol • increased HDL • increased triglyceride • fat restribution • hepatotoxicity • immune reconstitution syndrome |
| Instructions and dose (initial; typical) | 600mg once daily |
| Monitoring | • liver function tests • lipid profile |
| Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2015) |