Uses | • HIV-1 infection |
Contraindications, drug interactions or cautions | Contraindications • hypersensitivity to lamivudine Drug interactions • emtricitabine, ganciclovir-valganciclovir |
Adverse Effects (common and severe) | • headache • fatigue • anorexia • nausea • vomiting • diarrhea • myalgia • dizziness • neuropathy • insomnia • fat redistribution • immune reconsititution syndrome • lactic acidosis • hepatomegaly |
Instructions and dose (initial; typical) | 150 mg twice daily or 300 mg once daily |
Monitoring | • liver function test • HIV viral load • CD4 count • amylase • bilirubin |
Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2015) |