lamivudine

Uses• HIV-1 infection
Contraindications,
drug interactions
or cautions
Contraindications
• hypersensitivity to lamivudine
Drug interactions
• emtricitabine, ganciclovir-valganciclovir
Adverse Effects (common and severe)• headache
• fatigue
• anorexia
• nausea
• vomiting
• diarrhea
• myalgia
• dizziness
• neuropathy
• insomnia
• fat redistribution
• immune reconsititution syndrome
• lactic acidosis
• hepatomegaly
Instructions and dose
(initial; typical)
150 mg twice daily or 300 mg once daily
Monitoring• liver function test
• HIV viral load
• CD4 count
• amylase
• bilirubin
Source of Suggestion
WHO Model List of Essential Medicines
(Added on August, 2015)