Uses | • alcohol withdrawal syndrome • Wernicke's encephalopathy • beriberi(thiamine deficiency) • Korsakoffs syndrome |
Contraindications, drug interactions or cautions | Contraindications • hypersensitivity to thiamine |
Adverse Effects (common and severe) | • nausea • tightness of throat • weakness • pulmonary edema • restlessness • cyanosis • angioneurotic edema • pruritus, urticaria • diaphoresis • warmth |
Instructions and dose (initial; typical) | alcohol withdrawal syndrome: 100 mg/day intramuscular (IM) or intravenous (IV); Wernicke's encephalopathy: 100 mg IV, then 50-100 mg/day IM or IV until consuming a regular diet;Thiamine deficiency (beriberi): 5-30 mg/dose IM or IV 3 times/day |
Monitoring | |
Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2016) |