warfarin
| Uses | • atrial fibrillation • deep vein thrombosis • pulmonary embolism |
| Contraindications, drug interactions or cautions | Contraindications • pregnancy • active bleeding • hemorrhagic disorders • previous warfarin induced skin necrosis • recent surgery • noncompliant patients Drug Interactions • alcohol • allopurinol • amiodarone • cimetidine • fibrates • NSAIDs/Coxibs • phenobarbital • St. johns wort |
| Adverse Effects (common and severe) | • bleeding • bruising • nausea • diarrhea • abdominal cramping • fever |
| Instructions and dose (initial; typical) | 2mg; 2-10mg one time a day |
| Monitoring | liver function test |
| Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2015) |