acetaminophen

Adult
Uses
  • pain relief (available on site)
Contraindications,
drug interactions
or cautions
Contraindications
  • severe hepatic impairment or severe active liver disease
Drug interactions
  • cholestyramine, probenecid, alcohol, carbamazepine, isoniazid, lamotrigine
Cautions
  • limit acetaminophen dose to <4 g/day (adults)
  • use with caution in patients with alcoholic liver disease, known G6PD deficiency, hepatic impairment, or active liver disease.
Adverse Effects
(common and severe)
  • nausea
  • vomiting
  • acute liver failure
  • fatal skin reactions including Stevens-Johnson syndrome and toxic epidermal necrolysis
Instructions and dose
(initial; typical)
325-650mg three or four times a day
Monitoring
  • liver enzymes for chronic use
Source of Suggestion
WHO Model List of Essential Medicines (Added on August, 2015)