Uses | • pain relief • fever treatment • prevention of cardiovascular disease |
Contraindications, drug interactions or cautions | Contraindications • hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) • use in patients with asthma, rhinitis, and nasal polyps • use in children or teenagers for viral infections, with or without fever Drug interactions • apixaban, dabigatran, rivaroxaban, NSAIDs (COX-2 inhibitors or non-selective), vitamin K antagonist (warfarin), alcohol, ginkgo biloba, Varicella virus-containing vaccines Cautions • discontinue use if tinnitus or impaired hearing occurs • use with caution in patients with platelet and bleeding disorders • avoid use in patients with active peptic ulcer disease |
Adverse Effects (common and severe) | • upper gastrointestinal bleeding • tinnitus |
Instructions and dose (initial; typical) | 81mg daily |
Monitoring | • liver enzymes for chronic use |
Source of Suggestion | Suggestion from clinicians (Added on August, 2015) |