amoxicillin

Adult
Uses
  • bacterial infections (ear; nose; throat; genitourinary; lower respiratory tract; skin)
  • available on site
Contraindications,
drug interactions
or cautions
Contraindications
  • serious hypersensitivity to amoxicillin (e.g., anaphylaxis, Stevens-Johnson syndrome) or to other beta-lactams
Drug interactions
  • anticoagulants, macrolides, tetracyclines, sulfonamides, oral contraceptives, methotrexate
Cautions
  • dosage adjustment recommended for patients with renal impairment
  • prolonged use may result in fungal or bacterial superinfection, including C. difficile-associated diarrhea and pseudomembranous colitis
Adverse Effects
(common and severe)
  • nausea
  • vomiting
  • skin rash
  • clostridium difficile-associated diarrhea
Instructions and dose
(initial; typical)
indication-specific dosing (usual oral dosing range for mild to moderate infection: 250 every 8 hours or 500 mg every 12 hours)
Monitoring
  • monitor for signs of anaphylaxis during first dose
Source of Suggestion
WHO Model List of Essential Medicines (Added on August, 2015)