atorvastatin

Adult
Uses
  • hyperlipidemia
  • coronary artery disease
Contraindications,
drug interactions
or cautions
Contraindications
  • active liver disease, alcohol, pregnancy
Drug interactions
  • digoxin, warfarin, clarithromycin, erythromycin, gemfibrozil, grapefruit juice, verapamil
Cautions
  • use with caution in patients with advanced age or renal impairment (these patients are predisposed to myopathy)
Adverse Effects
(common and severe)
  • diarrhea
  • arthralgia
  • nasopharyngitis
  • increased serum transaminases
  • myopathy
  • rhabdomyolysis
Instructions and dose
(initial; typical)
10 to 80 mg once daily (doses should be individualized according to the baseline LDL-cholesterol concentrations)
Monitoring
  • lipid panel (total cholesterol; HDL; LDL; triglyceride)
  • liver transaminases levels
  • creatine phosphokinase (CPK)
Source of Suggestion
Suggestion from clinicians (Added on August, 2015)