atorvastatin
| Uses | • hyperlipidemia • coronary artery disease |
| Contraindications, drug interactions or cautions | Contraindications • active liver disease, alcohol, pregnancy Drug interactions • digoxin, warfarin, clarithromycin, erythromycin, gemfibrozil, grapefruit juice, verapamil Cautions • use with caution in patients with advanced age or renal impairment (these patients are predisposed to myopathy) |
| Adverse Effects (common and severe) | • diarrhea • arthralgia • nasopharyngitis • increased serum transaminases • myopathy • rhabdomyolysis |
| Instructions and dose (initial; typical) | 10 to 80 mg once daily (doses should be individualized according to the baseline LDL-cholesterol concentrations) |
| Monitoring | • lipid panel (total cholesterol; HDL; LDL; triglyceride) • liver transaminases levels • creatine phosphokinase (CPK) |
| Source of Suggestion | Suggestion from clinicians (Added on August 2015) |