Uses | • Parkinson's disease • drug-induced parkinsonian symptoms or dystonic reactions |
Contraindications, drug interactions or cautions | Contraindications • hypersensitivity, angle-closure glaucoma, myasthenia gravis Drug interactions • phenothiazines, haloperidol or other drugs with anticholinergic/antidopaminergic activity, cholinesterase inhibitors, potassium chloride supplements |
Adverse Effects (common and severe) | • tachycardia • paralytic ileus • constipation • nausea • vomiting • dry mouth • toxic psychosis • blurred vision • dilated pupils • urinary retention • dysuria • allergic reaction • heat stroke • hyperthermia • fever |
Instructions and dose (initial; typical) | Parkinson's disease: initial dose 0.5-1mg daily; usual dose 1-2mg twice daily; max dose 6mg/day Parkinsonian symptoms: 1-4mg once or twice daily |
Monitoring | |
Source of Suggestion | Commonly prescribed medication (Added on March, 2016) |