dolutegravir

Uses• antiviral: HIV-1 infection
Contraindications,
drug interactions
or cautions		Contraindications
• CI:hypersensitivity to dolutegravir, concurrent use with dofetilide
Drug interactions
• phenytoin, phenobarbital, primidone, St. John's Wort
Adverse Effects (common and severe)• fatigue
• malaise
• fat redistribution
• immune reconstitiution syndrome
• increased liver enzymes
Instructions and dose
(initial; typical)		50mg once daily
Monitoring• viral load
• CD4 count
• lipid profile
• liver function tests
Source of Suggestion
Suggestion from clinicians (Added on August, 2015)