dolutegravir

Adult
Uses
  • antiviral: HIV-1 infection
Contraindications,
drug interactions
or cautions
Contraindications
  • CI:hypersensitivity to dolutegravir, concurrent use with dofetilide
Drug interactions
  • phenytoin, phenobarbital, primidone, St. John's Wort
Adverse Effects
(common and severe)
  • fatigue
  • malaise
  • fat redistribution
  • immune reconstitiution syndrome
  • increased liver enzymes
Instructions and dose
(initial; typical)
50mg once daily
Monitoring
  • viral load
  • CD4 count
  • lipid profile
  • liver function tests
Source of Suggestion
Suggestion from clinicians (Added on June, 2016)