efavirenz

Adult
Uses
  • antiviral: HIV-1 infection
Contraindications,
drug interactions
or cautions
Contraindications
  • hypersensitivity to efavirenz (Stevens-Johnson syndrome, erythema multiforme, toxic skin eruptions)
Drug interactions
  • cabamazepine, itraconzole, ketoconazole, nisoldipin
Adverse Effects
(common and severe)
  • dizziness
  • fever
  • depression
  • insomnia
  • skin rash
  • increased serum cholesterol
  • increased HDL
  • increased triglyceride
  • fat restribution
  • hepatotoxicity
  • immune reconstitution syndrome
Instructions and dose
(initial; typical)
600 mg once daily
Monitoring
  • liver function tests
  • lipid profile
Source of Suggestion