hydroxychloroquine
| Uses | • rheumatoid arthritis • lupus erythematosus • malaria |
| Contraindications, drug interactions or cautions | Contraindications • preexisting retinopathy • use in children <6 years or weighing <35 kg Drug interactions • phenothiazines, beta blockers, dapsone |
| Adverse Effects (common and severe) | • headache • seizure • diarrhea • nausea • vomiting • anemia • leukopenia • thrombocytopenia • hepatic infussificency • angioedema • myopathy • visual disturbances • blurred vision • photophobia • decreased visual acuity • tinnitus • bronchospasm |
| Instructions and dose (initial; typical) | 400 to 600 mg once daily |
| Monitoring | • complete blood count • liver function tests • ophthalmologic exam • muscle strength during long-term therapy |
| Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2015) |