Uses | • menopause |
Contraindications, drug interactions or cautions | Contraindications • breast malignancy, hepatic disease, thromboembolism Cautions • increased risk of deep vein thrombosis, pulmonary embolism and myocardial infarction |
Adverse Effects (common and severe) | • abnormal uterine bleeding • amenorrhea • breast tenderness • thromboembolic disorders • nausea |
Instructions and dose (initial; typical) | 150mg intramuscularly or 104mg subcutaneuous every 3 months |
Monitoring | • thyroid stimulating hormone |
Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2015) |