metformin

Uses• diabetes mellitus type 2
Contraindications,
drug interactions
or cautions
Contraindications
• CrCl lower than 30ml/min, acute decompensted heart failure, liver dysfunction, 48 hours post-iodinated contrast media
Drug interactions
• alcohol, cimetidine
Cautions
• caution if CrCL is lower than 60ml/min
Adverse Effects (common and severe)• weight loss
Instructions and dose
(initial; typical)
250mg; 500mg-850mg twice a day
Monitoring• glucose
• urine ketones
Source of Suggestion
WHO Model List of Essential Medicines
(Added on August, 2015)