metformin

Adult
Uses
  • diabetes mellitus type 2
Contraindications,
drug interactions
or cautions
Contraindications
  • CrCl lower than 30ml/min, acute decompensted heart failure, liver dysfunction, 48 hours post-iodinated contrast media
Drug interactions
  • alcohol, cimetidine
Cautions
  • caution if CrCL is lower than 60ml/min
Adverse Effects
(common and severe)
  • weight loss
Instructions and dose
(initial; typical)
250mg; 500mg-850mg twice a day
Monitoring
  • glucose
  • urine ketones
Source of Suggestion