pravastatin
| Uses | • primary hypercholesterolemia • combined hyperlipidemia • prevention of cardiovascular events |
| Contraindications, drug interactions or cautions | Contraindications • active liver disease • alcohol • pregnancy Drug Interactions • digoxin • niacin • fibric acid derivatives |
| Adverse Effects (common and severe) | • headache • rash • abdominal cramps • diarrhea • nausea • vomiting |
| Instructions and dose (initial; typical) | 40 mg daily |
| Monitoring | • lipid panel (total cholesterol; HDL; LDL; triglyceride) • hepatic transaminase levels • ceatine phosphokinase (CPK) |
| Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2015) |