propylthiouracil

Adult
Uses
  • hyperthyroidism
  • Graves’ disease
  • thyrotoxic crisis/thyroid storm
Contraindications,
drug interactions
or cautions
Contraindications
  • liver disease
Drug interactions
  • warfarin, digoxin, beta blockers
Adverse Effects
(common and severe)
  • lupus like vasculitis
  • agranulocytosis
  • severe liver disease
Instructions and dose
(initial; typical)
100mg; 100-300mg one time a day
Monitoring
  • thyroid stimulating hormone (TSH)
  • complete blood count
  • liver function test
Source of Suggestion