sulfamethoxazole/ trimethoprim

Uses• bacterial infections: acute otitis media, bronchiectasis, bronchitis (acute on chronic), enteritis, pertussis (3rd line), P. jirovecipneumonia
• skin infections
• sinusitis
• travellers diarrhea
• urinary tract infections (available on site)
Contraindications,
drug interactions
or cautions		Contraindications
• sulphur
• trimethoprim allergy
• pregnancy
• infants less than 2 months
• folic acid deficiency
Drug Interactions
• phenytoin
• tricyclic antidepressants
• anticoagulants
• angiotensin-converting-enzyme inhibitors
Adverse Effects (common and severe)• nausea
• vomiting
• anorexia
• allergic skin reactions
Instructions and dose
(initial; typical)		5-10mg/kg/day in 2 divided doses
Monitoringrenal function tests in elderly
Source of Suggestion
WHO Model List of Essential Medicines (Added on August, 2015)