sulfamethoxazole/ trimethoprim

Adult
Uses
  • bacterial infections: acute otitis media
  • bronchiectasis
  • bronchitis (acute on chronic)
  • enteritis
  • pertussis (3rd line)
  • P. jirovecipneumonia
  • skin infections
  • sinusitis
  • travellers diarrhea
  • urinary tract infections (available on site)
Contraindications,
drug interactions
or cautions
Contraindications
  • CI: sulphur, trimethoprim allergy, pregnancy, infants less than 2 months, folic acid deficiency
Drug interactions
  • phenytoin, tricyclic antidepressants, anticoagulants, angiotensin-converting-enzyme inhibitors
Adverse Effects
(common and severe)
  • nausea
  • vomiting
  • anorexia
  • allergic skin reactions
Instructions and dose
(initial; typical)
5-10mg/kg/day in 2 divided doses
Monitoring
  • renal function tests in elderly
Source of Suggestion