trimethoprim
| Uses | • urinary tract infections - acute uncomplicated (available on site) • conjunctivitis (see polymyxin B) |
| Contraindications, drug interactions or cautions | Contraindications • pregnancy, breast feeding • children under 12 years • impaired kidney or liver function • megaloblastic anemia Drug Interactions • phenytoin |
| Adverse Effects (common and severe) | • anemia • thrombocytopenia • neutropenia • nausea • vomiting • abdominal discomfort |
| Instructions and dose (initial; typical) | 100mg; 100mg every 12 hours |
| Monitoring | • complete blood count • renal function tests |
| Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2016) |