abacavir
| Uses | • HIV-1 infection |
| Contraindications, drug interactions or cautions | Contraindications • hypersensitivity to abacavir Drug interactions • protease inhibitors, ganciclovir, methadone, ribavirin Cautions • abacavir should always be used as a component of a multidrug regimen |
| Adverse Effects (common and severe) | • fat redistribution • immune reconstitution syndrome • lactic acidosis • hepatomegaly • fatigue • malaise • nausea |
| Instructions and dose (initial; typical) | 300 mg twice daily or 600 mg once daily in combination with other antiretroviral agents |
| Monitoring | • CD4 count • HIV RNA plasma levels • complete blood count • serum creatine kinase • serum • transaminases • triglycerides • serum amylase |
| Source of Suggestion | Suggestion from clinicians (Added on June, 2016) |