levonorgestrel – releasing intrauterine system
| Uses | • idiopathic menorhagia |
| Contraindications, drug interactions or cautions | Contraindications • uterine or liver malignancy, pregnancy, pelvic inflammatory disease, cervicitis, undiagnosed abnormal uterine bleeding, immunodeficiency, bacterial endocarditis Drug interactions • primidone, barbiturates, phenytoin, carbamazepine, rifampicin, griseofulvin Cautions • caution with migraines |
| Adverse Effects (common and severe) | • increased risk of cardiovascular events including thrombosis • breast cancer • uterine bleeding iregularities |
| Instructions and dose (initial; typical) | single device 52mg |
| Monitoring | |
| Source of Suggestion | WHO Model List of Essential Medicines (Added on August, 2015) |